MFT: Abbott Ltd
SALT COMPOSITION: Methylcobalamin1500mcg + Pregabalin 75mg
STORAGE: Store at room temperature
PRICE: For one strip (inclusive all taxes)
Packing: 1 Strip of 10 tablets each
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Category :Pain Management
Stock : 500
Pregamet SR Tablet is a Fixed-dose Drug Combination (FDC) medicine prescribed under the schedule H drug, used in the treatment of neuropathic pain. This FDC tablet relief the pain by modulating the calcium channel activity of the nerve cells. This medicine also protects nerve fibers and healing damaged nerve cells.
This FDC Sustained Release (SR) tablet / Control Release (CR) tablet is taken orally with or without a meal, preferably at the bedtime of every day, should be taken at the same time every day. With this fixed-dose schedule, you can maintain a consistent level of medicine in the blood and targeted site as well.
You should take this FDC as advised by your doctor/pharmacist. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
This FDC tablet is used for the treatment of “NEUROPATHIC PAIN” due to diabetes, spinal Injuries. Take this FDC SR tablet in the dose and duration as advised by your doctor/pharmacist. Swallow it. Do not chew, crush, or break it.
This FDC SR tablet is greatly beneficial to treat chronic pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It helps to reduce pain and associated symptoms such as mood changes, sleep disorders (insomnia), and tiredness. Pregabalin, an active ingredient of this FDC tablet is acting by interfering with pain signals that travel through the damaged nerves and the brain. It also contains methylcobalamin as nutritional supplements that improve nerve conduction. Taking this FDC tablet regularly helps in improving physical and social functioning and overall, your quality of life.
Some common side effects of this medicine such as dizziness and sleepiness, so do not drive or do anything that requires mental attention. Most of the side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor/pharmacist if they persist.
COMMON SIDE EFFECTS:
These side effects are mild in nature and get improve with time. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor/pharmacist if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
MODE OF ACTION / PHARMACOLOGY OF METHYLCOBALAMIN AND PREGABALIN
The nerve can send false messages to your brain. The brain thinks that a part of your body is being hurt when it is not. This makes you feel pain. By altering the way nerves work, pregabalin may reduce your pain. Pregabalin subtly reduces the synaptic release of several neurotransmitters, apparently by binding to alpha2-delta subunits.
Methylcobalamin helps in the synthesis of neuronal lipids, regeneration of axonal nerves, and has neuroprotective activity, which promotes neurons to function in a proper way and thus improves neuropathic syndromes such as neuropathic pain. It is an approved treatment for peripheral neuropathy